There is a very recent publication in collaboration with Tobias Marschall and his group at the MPI in Saarbrücken in Bioinformatics on a new algorithm called SaaRclust for de novo assembly. SaaRclust aligns single-cell Strand-seq data directly onto long reads to perform an in silico separation of the data into chromosomes prior to assembly. By using the directionality of Strand-seq they clustered long sequencing reads by chromosomal origin and haplotype.
In a new publication on childhood medullobastoma in Lancet Oncology we propose criteria for routine genetic screenings based on clinical and molecular tumour characteristics. Please also see the feature on the EMBL webpage here. This work resulted from a large international collaboration with researchers e.g. from St. Jude Children’s Research Hospital in Memphis, and Hopp Children’s Cancer Center at the NCT Heidelberg (KiTZ).